ADHD Medication Pregnancy: The Good The Bad And The Ugly
adhd focus medication Medication During Pregnancy and Breastfeeding
Women suffering from ADHD have to make a difficult choice on whether to keep or stop taking ADHD medication during pregnancy and breast-feeding. Little data exists about how long-term exposure to these drugs could affect the fetus.
A study recently published in Molecular Psychiatry shows that children exposed to ADHD medication during the uterus don't develop neurological conditions like hearing loss or impaired vision seizures, febrile seizures, or IQ impairment. The authors acknowledge that more high quality research is needed.
Risk/Benefit Analysis
Women who are pregnant and take ADHD medication must consider the benefits of taking it versus the dangers for the baby. Doctors don't have the data needed to make unequivocal recommendations but they can provide information on risks and benefits that aid pregnant women in making informed choices.
A study published in Molecular Psychiatry concluded that women who were taking ADHD medication during early pregnancy were not at greater risk of fetal malformations or structural birth defects. Researchers used a large sample-based case control study to compare the incidence of major structural defects in infants born to mothers who took stimulants during pregnancy. Pediatric cardiologists and clinical geneticists reviewed the cases to ensure an accurate case classification and to limit the possibility of bias.
However, the study was not without its flaws. The most important issue was that they were not able to differentiate the effects of the medication from those of the underlying disorder. This limitation makes it difficult for researchers to establish whether the small differences observed between the groups exposed were due to the use of medication, or if they were confounded by co-morbidities. Researchers also did not study long-term outcomes for offspring.
The study did reveal that infants whose mothers took ADHD medication during pregnancy were at a more risk of being admitted to the neonatal intensive care unit (NICU) than infants whose mothers had not taken any medication or stopped their medications before or during pregnancy. The reason for this was central nervous system disorders. The increased risk of admission was not affected by the stimulant medication used during pregnancy.
Women who were taking stimulant Adhd medication private prescription medication during pregnancy were also at an increased risk of having a caesarean section or having a baby born with a low Apgar score (less than 7). These risks did not appear to be influenced by the kind of medication used during pregnancy.
Researchers suggest that the small risk of using ADHD medications in early pregnancies can be offset by more beneficial outcomes for both mother and baby from continuing treatment for the woman's condition. Physicians should discuss the issue with their patients and, if possible, help them develop strategies to improve coping skills that can lessen the effects of her disorder on her daily functioning and relationships.
Medication Interactions
Doctors are increasingly confronted with the dilemma of whether to continue treatment or stop during pregnancy as more women are diagnosed with ADHD. These decisions are often made without clear and authoritative evidence. Instead, physicians must consider their own expertise and experience, as well as the experiences of other doctors, and the research on the topic.
Particularly, the subject of possible risks to the infant can be difficult. The research that has been conducted on this topic is based on observation rather than controlled studies and many of the findings are in conflict. Additionally, the majority of studies limit their analysis to live births, which could underestimate severe teratogenic effects that result in abortion or termination of the pregnancy. The study that is discussed in the journal club addresses these issues by analyzing information on deceased and live births.
The conclusion The conclusion: While certain studies have demonstrated an association between ADHD medications and the risk of certain birth defects, other studies have found no such relationship, and most studies have a neutral or slight negative effect. In the end, a careful risk/benefit assessment must be conducted in every instance.
For women suffering from ADHD and ADD, the decision to stop medication is difficult, if not impossible. In a recent article published in Archives of Women's Mental Health by psychologist Jennifer Russell, she notes that stopping ADHD medications during pregnancy can increase depression and feelings of loneliness. The loss of medication can affect the ability to safely drive and perform work-related tasks, which are vital aspects of normal life for people with best adhd medication uk.
She recommends women who are unsure about whether to keep or stop taking medication because of their pregnancy consider informing family members, friends and colleagues on the condition, its impact on daily life, and the advantages of continuing the current treatment regimen. It can also help women feel more confident in her decision. It is also worth noting that certain medications can pass through the placenta so if a woman decides to discontinue her ADHD medication during pregnancy and breastfeeding, she must be aware that traces of the medication could be transferred to the child.
Birth Defects Risk
As the use of ADHD medications to treat symptoms of attention deficit hyperactivity disorder (ADHD) increases as do concerns about what impact the drugs might have on fetuses. Recent research published in the journal Molecular Psychiatry has added to the body of knowledge regarding this topic. Researchers utilized two massive data sets to examine more than 4.3 million pregnancies and determine if the use of stimulant medications caused birth defects. Although the risk overall is low, the researchers discovered that the first-trimester exposure to ADHD medicines was associated with an increase in the risk of certain heart defects like ventriculo-septal defects (VSD).
The authors of the study didn't discover any link between the use of early medications and congenital anomalies like facial deformities or club feet. The results are in the same vein as previous studies which showed an insignificant, but small increase in the number of cardiac malformations among women who started taking adhd medication without diagnosis uk medication before the time of pregnancy. The risk increased in the latter stages of pregnancy, when a lot of women began to stop taking their medication.
Women who took ADHD medications during the first trimester of their pregnancy were also more likely to experience a caesarean section, a low Apgar score following delivery, and a baby that required breathing assistance at birth. The researchers of the study were not able to eliminate bias due to selection because they limited their study to women who did not have any other medical conditions that might have contributed to the findings.
The researchers hope that their research will serve to inform the clinical decisions of doctors who see pregnant women. They suggest that although discussing the benefits and risks is important but the decision to stop or maintain medication should be based on each woman's requirements and the severity of her ADHD symptoms.
The authors also advise that while discontinuing the medications is an option, it isn't an option to consider due to the high incidence of depression and other mental health issues in women who are pregnant or who are recently post-partum. Additionally, research suggests that women who stop taking their medications will have a tough transitioning to life without them once the baby is born.
Nursing
The responsibilities that come with being a new mother can be overwhelming. Women with ADHD who must work through their symptoms while attending physician appointments as well as making preparations for the arrival of a child and adapting to new routines in the home may face a lot of challenges. As such, many women choose to continue taking their ADHD medications throughout the course of pregnancy.
The majority of stimulant medications are absorbed through breast milk in very small amounts, therefore the risk to the breastfeeding infant is minimal. The rate of exposure to medication can vary depending upon the dosage, frequency of administration and the time of day. In addition, individual medications enter the infant's system differently through the gastrointestinal tract and breast milk, and the effect of this on a newborn is not fully understood.
Due to the absence of evidence, some doctors may recommend stopping stimulant medications during the pregnancy of a woman. This is a complicated decision for the patient, who must balance the benefits of keeping her medication against the potential risks to the foetus. In the meantime, until more information is available, doctors should ask all pregnant patients about their experience with ADHD and if they plan or are taking to take medication during the perinatal time.
Numerous studies have proven that women can continue to take their ADHD medication without risk during pregnancy and breast-feeding. In the end, an increasing number of patients are choosing to do so and, in consultation with their physician, they have discovered that the benefits of keeping their current medication far exceed any risk.
Women with ADHD who are planning to breastfeed should seek advice from an expert psychiatrist prior to becoming pregnant. They should review their medications with their prescriber and discuss the pros and cons of continued treatment, including non-pharmacological strategies. Psychoeducation is also needed to help pregnant women with treating adhd without medication understand the symptoms and underlying disorder. They should also learn about treatment options and strengthen strategies for coping. This should be a multidisciplinary approach including obstetricians, GPs and psychiatry. Pregnancy counseling should include discussion of a treatment plan for the mother and child, as well as monitoring for indicators of deterioration, and, if needed adjustments to the medication regimen.